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Authors: Dandan Wang 1 ; Yu Han 1 ; Jie Sun 2 and Dejian Huang 3

Affiliations: 1 National University of Singapore Suzhou Institute, Suzhou and China, China ; 2 National University of Singapore Suzhou Institute, Suzhou, China, Department of Industrial Design, Xi'an Jiaotong-Liverpool, Suzhou and China, China ; 3 National University of Singapore Suzhou Institute, Suzhou, China, Department of Chemistry, National University of Singapore and Singapore, Singapore

Keyword(s): microsphere, electrospray, polycaprolactone, drug delivery

Abstract: In controlled drug release systems, biodegradable and biocompatible polymer microspheres are good candidates as drug carrier due to their large surface area. Here, we used the electrospraying technique to fabricate polycaprolactone microspheres. By exploring the process parameters systematically, microspheres with different morphology were produced. The increase of feed rate increased the particle size and collapse of the particle, a feed rate of 0.2 μL/min was found to produce narrow size distributed microspheres with the average size of ~4 μm. Our study shows that electrospray is a promising technique to fabricate microspheres applied in controlled drug delivery systems.

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Paper citation in several formats:
Wang, D.; Han, Y.; Sun, J. and Huang, D. (2019). Microsphere Fabrication of Polycaprolactone via Electrospray: Effect of Different Parameters. In The Second International Conference on Materials Chemistry and Environmental Protection - MEEP; ISBN 978-989-758-360-5, SciTePress, pages 5-9. DOI: 10.5220/0008184500050009

@conference{meep19,
author={Dandan Wang. and Yu Han. and Jie Sun. and Dejian Huang.},
title={Microsphere Fabrication of Polycaprolactone via Electrospray: Effect of Different Parameters},
booktitle={The Second International Conference on Materials Chemistry and Environmental Protection - MEEP},
year={2019},
pages={5-9},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008184500050009},
isbn={978-989-758-360-5},
}

TY - CONF

JO - The Second International Conference on Materials Chemistry and Environmental Protection - MEEP
TI - Microsphere Fabrication of Polycaprolactone via Electrospray: Effect of Different Parameters
SN - 978-989-758-360-5
AU - Wang, D.
AU - Han, Y.
AU - Sun, J.
AU - Huang, D.
PY - 2019
SP - 5
EP - 9
DO - 10.5220/0008184500050009
PB - SciTePress

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