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Authors: Aleksandar Jeremic 1 ; D. Nikolic 2 ; G. Djuricic 3 ; N. Milcanovic 3 and Z. Jokovic 3

Affiliations: 1 Department of Electrical and Computer Engineering, McMaster University, Hamilton, ON, Canada ; 2 University Children’s Hospital, Faculty of Medicine, University of Belgrade, Serbia ; 3 Department of Radiology, University Children’s Hospital, Belgrade, School of Medicine, University of Belgrade, Serbia

Keyword(s): Source Localization, Electroencephalography, Inverse Models.

Abstract: Source localization of electrical activity in newborn infants is important from two standpoints. From an academic standpoint such insights can enable better understanding of brain development and from clinical standpoint localization of electrical activity can identify regions of the brain with higher than usual activity and possibly improve possible treatment outcomes. The electrical activity and the corresponding electroencephalography (EEG) measurements are dependant on electrical properties of brain and skull tissue i.e. corresponding conductivities and geometry. In this paper we investigate effects of realistic geometry in newborn infants by accounting for soft spots (fontanels) that are present in newborn infants. These structures have larger conductivity than regular bone tissue and hence the estimation accuracy can potentially be improved by optimally positioning EEG sensors on the surface of the skull. We generate forward model using realistic geometry and finite-element mod el generated by COMSOL. We utilize simplified source model consisting of single dipole source and calculate corresponding Cramer-Rao bound as a function of source intensity and locations. (More)

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Paper citation in several formats:
Jeremic, A.; Nikolic, D.; Djuricic, G.; Milcanovic, N. and Jokovic, Z. (2024). Cramer-Rao Bound for Dipole Source Localization in Infants Using Realistic Geometry. In Proceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOSIGNALS; ISBN 978-989-758-688-0; ISSN 2184-4305, SciTePress, pages 807-810. DOI: 10.5220/0012470200003657

@conference{biosignals24,
author={Aleksandar Jeremic. and D. Nikolic. and G. Djuricic. and N. Milcanovic. and Z. Jokovic.},
title={Cramer-Rao Bound for Dipole Source Localization in Infants Using Realistic Geometry},
booktitle={Proceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOSIGNALS},
year={2024},
pages={807-810},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0012470200003657},
isbn={978-989-758-688-0},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the 17th International Joint Conference on Biomedical Engineering Systems and Technologies - BIOSIGNALS
TI - Cramer-Rao Bound for Dipole Source Localization in Infants Using Realistic Geometry
SN - 978-989-758-688-0
IS - 2184-4305
AU - Jeremic, A.
AU - Nikolic, D.
AU - Djuricic, G.
AU - Milcanovic, N.
AU - Jokovic, Z.
PY - 2024
SP - 807
EP - 810
DO - 10.5220/0012470200003657
PB - SciTePress