Authors:
Iulia Clitan
1
;
Corneliu Lungoci
2
;
Vlad Muresan
1
;
Daniel Moga
1
and
Valentin Sita
1
Affiliations:
1
Technical University of Cluj-Napoca, Romania
;
2
„Iuliu Hatieganu“ University of Medicine and Pharmacy Cluj-Napoca, Romania
Keyword(s):
Cytoreductive Surgery, Regional Chemotherapy, Hyperthermic Intraperitioneal Chemotherapy (HIPEC) Equipment, Temperature Control, Strejc Identification Method, Robust Control, H∞ Controller.
Related
Ontology
Subjects/Areas/Topics:
Control and Supervision Systems
;
Informatics in Control, Automation and Robotics
;
Modeling, Simulation and Architectures
;
Robotics and Automation
;
Signal Processing, Sensors, Systems Modeling and Control
;
System Modeling
Abstract:
This paper presents an advanced control structure for controlling the heating process of cytostatic solution used in regional chemotherapy. The solution temperature control is an individual control structure which is desired to be implemented on hyperthermic intraperitioneal chemotherapy (HIPEC) innovative device. Cytoreductive surgery followed by HIPEC represents a therapeutic solution for patients suffering from peritoneal carcinomatosis, an abdominal cancer. An H∞ robust control structure is designed since the heating process model’s parameters depend on the solution’s delivery flow. It is considered that the heating process gain can vary from a nominal value to a maximum value, which represents an increase by up to 100% from the nominal value. The responses to a step input signal for the nominal case, and the cases when the gain varies by 50% or 100%, are simulated. The control structure is compared against a PID feasible controller by means of overall performances. It resulted t
hat the robust controller generates the best performance set for the nominal gain and also for the case when the heating process gain varies.
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