Optical Technology for Ultraviolet Erythema Assessment and Minimal Erythema Dose Determination in Healthy Volunteers

Mikhail Makmatov-Rys, Alexey Glazkov, Irina Raznitsyna, Dmitriy Kulikov, Anton Molochkov, Albina Khlebnikova, Ekaterina Kaznacheeva, Alexey Sekirin, Dmitry Rogatkin

Abstract

Currently, in clinical practice, the assessment of ultraviolet (UV) -induced erythema and the determination of the minimal erythema dose (MED) is done visually, which is subjective, inaccurate and associated with high variability of the results. To solve this problem, the application of optical methods seems promising, allowing us to evaluate changes in epidermis and dermis induced by UV exposure. In this study the analysis of endogenous fluorescence and microcirculation characteristics by non-invasive optical methods revealed the relationship between the intensity of endogenous fluorescence of porphyrins and oxygen consumption with a dose of UV radiation. The correlation of the intensity of endogenous fluorescence of the irradiated region normalized to intact tissue with a dose of UV was demonstrated. Therefore, optical diagnostic methods can be a promising tool for non-invasive and quantitative assessment of UV erythema and MED.

Download


Paper Citation


in Harvard Style

Makmatov-Rys M., Glazkov A., Raznitsyna I., Kulikov D., Molochkov A., Khlebnikova A., Kaznacheeva E., Sekirin A. and Rogatkin D. (2020). Optical Technology for Ultraviolet Erythema Assessment and Minimal Erythema Dose Determination in Healthy Volunteers.In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, ISBN 978-989-758-398-8, pages 73-78. DOI: 10.5220/0009177000730078


in Bibtex Style

@conference{biodevices20,
author={Mikhail Makmatov-Rys and Alexey Glazkov and Irina Raznitsyna and Dmitriy Kulikov and Anton Molochkov and Albina Khlebnikova and Ekaterina Kaznacheeva and Alexey Sekirin and Dmitry Rogatkin},
title={Optical Technology for Ultraviolet Erythema Assessment and Minimal Erythema Dose Determination in Healthy Volunteers},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,},
year={2020},
pages={73-78},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009177000730078},
isbn={978-989-758-398-8},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,
TI - Optical Technology for Ultraviolet Erythema Assessment and Minimal Erythema Dose Determination in Healthy Volunteers
SN - 978-989-758-398-8
AU - Makmatov-Rys M.
AU - Glazkov A.
AU - Raznitsyna I.
AU - Kulikov D.
AU - Molochkov A.
AU - Khlebnikova A.
AU - Kaznacheeva E.
AU - Sekirin A.
AU - Rogatkin D.
PY - 2020
SP - 73
EP - 78
DO - 10.5220/0009177000730078