Gene Co-expression Analysis for Lung Cancer Biomarkers Detection

Stefani Kostadinovska, Slobodan Kalajdziski, Monika Simjanoska

Abstract

Cancer is one of the most widespread diseases that we come across. The complexity of this disease makes it difficult to analyze and detect biomarkers with the purpose to ease the targeted treatments. This study presents a methodology based on gene expression data that provides promising results in terms of revealing potential biomarkers associated with lung cancer. To accomplish this, gene networks are built presenting the correlation among the genes. These networks are further analyzed and thus specific modules are created. Hereupon special representative genes for each of the modules are detected that lead to the identification of potential biomarkers for lung cancer. The reliability of the revealed biomarkers has been proved in the literature.

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Paper Citation


in Harvard Style

Kostadinovska S., Kalajdziski S. and Simjanoska M. (2020). Gene Co-expression Analysis for Lung Cancer Biomarkers Detection.In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 3: BIOINFORMATICS, ISBN 978-989-758-398-8, pages 60-67. DOI: 10.5220/0009176400600067


in Bibtex Style

@conference{bioinformatics20,
author={Stefani Kostadinovska and Slobodan Kalajdziski and Monika Simjanoska},
title={Gene Co-expression Analysis for Lung Cancer Biomarkers Detection},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 3: BIOINFORMATICS,},
year={2020},
pages={60-67},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009176400600067},
isbn={978-989-758-398-8},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 3: BIOINFORMATICS,
TI - Gene Co-expression Analysis for Lung Cancer Biomarkers Detection
SN - 978-989-758-398-8
AU - Kostadinovska S.
AU - Kalajdziski S.
AU - Simjanoska M.
PY - 2020
SP - 60
EP - 67
DO - 10.5220/0009176400600067