Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices

Alžbeta Bohiniková, Inês Maia, Monika Smiešková, Alžbeta Bugáňová, Ana Moita, Ivan Cimrák, Rui Lima

Abstract

This article describes the overview of the steps required to derive and validate a new model on cell behaviour in microfluidic devices, from the experimental approach to the computational model. The paper identifies the challenges of the biological side of the experiments and shows where computational power can be useful. It also emphasizes the necessity for the collaboration between the experimental and computational research groups. Computations can offer great insides into the mechanics of cells, however, interesting applications mainly arise from combining nunerics with experiments. Well calibrated and verified model can be used to improve the performance of a given microfluidic device by testing various geometries and thus lowering the number of devices that need to be produced. Choosing several designs of microfluidic devices one tries to demonstrate the wide range of possible uses of the microfluidic technology and how the computations can enrich them.

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Paper Citation


in Harvard Style

Bohiniková A., Maia I., Smiešková M., Bugáňová A., Moita A., Cimrák I. and Lima R. (2020). Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices.In Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, ISBN 978-989-758-398-8, pages 280-287. DOI: 10.5220/0009173202800287


in Bibtex Style

@conference{biodevices20,
author={Alžbeta Bohiniková and Inês Maia and Monika Smiešková and Alžbeta Bugáňová and Ana Moita and Ivan Cimrák and Rui Lima},
title={Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices},
booktitle={Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,},
year={2020},
pages={280-287},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009173202800287},
isbn={978-989-758-398-8},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,
TI - Assessment of Computational Cell Model Benefits for Optimization of Microfluidic Devices
SN - 978-989-758-398-8
AU - Bohiniková A.
AU - Maia I.
AU - Smiešková M.
AU - Bugáňová A.
AU - Moita A.
AU - Cimrák I.
AU - Lima R.
PY - 2020
SP - 280
EP - 287
DO - 10.5220/0009173202800287