The Impact of Probiotic Therapy on the Levels of Butyrate Acid in Inflammatory Bowel Disease

Fauzi Yusuf, Wahyuddin, Azzaki Abubakar, Siti Adewiyah

2018

Abstract

Inflammatory bowel disease (IBD) is a term applied to a group of bowel disorders in which inflammation is a major feature, it is widely accepted that these diseases have long been associated with imbalances in mucosal levels of micro-flora-produced short-chain fatty acids such as butyrate. 10 Patients received a 2 –week probiotic treatment and 10 control patients received a placebo for the same period. For the pre- and post-intervention assessments, stool samples were analysed for their level of butyrate acid with gas chromatography. This study showed that the mean concentration of butyrate acids in pre- and post- probiotic therapy was 6.49 ±2.64 versus 21.07 ±8.01 umol/g. Compared to the group who received the placebo, the group who received the probiotic therapy showed a significant increase in the level of butyrate acid ( P < 0.001). Future research should be done to study the effects of the therapy with larger samples over longer periods.

Paper Citation

in Harvard Style

Yusuf F., Wahyuddin., Abubakar A. and Adewiyah S. (2018). The Impact of Probiotic Therapy on the Levels of Butyrate Acid in Inflammatory Bowel Disease.In Proceedings of the 2nd Syiah Kuala International Conference on Medicine and Health Sciences - Volume 1: SKIC-MHS, ISBN 978-989-758-438-1, pages 81-84. DOI: 10.5220/0008791300810084

in Bibtex Style

@conference{skic-mhs18,
author={Fauzi Yusuf and Wahyuddin and Azzaki Abubakar and Siti Adewiyah},
title={The Impact of Probiotic Therapy on the Levels of Butyrate Acid in Inflammatory Bowel Disease},
booktitle={Proceedings of the 2nd Syiah Kuala International Conference on Medicine and Health Sciences - Volume 1: SKIC-MHS,},
year={2018},
pages={81-84},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008791300810084},
isbn={978-989-758-438-1},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd Syiah Kuala International Conference on Medicine and Health Sciences - Volume 1: SKIC-MHS,
TI - The Impact of Probiotic Therapy on the Levels of Butyrate Acid in Inflammatory Bowel Disease
SN - 978-989-758-438-1
AU - Yusuf F.
AU - Wahyuddin.
AU - Abubakar A.
AU - Adewiyah S.
PY - 2018
SP - 81
EP - 84
DO - 10.5220/0008791300810084