Anti-Adipogenic Activity of Fractions of Guazuma ulmifolia Leaf

Nuri, Bambang Prajogo, Sukardiman

Abstract

Objective: This study purposed to investigate the anti-adipogenic activity of the chloroform, ethyl acetate, and residual ethanol fractions of Guazuma ulmifolia leaf extract. Methods: The fractionation of ethanol extract was carried out by solvent-solvent partition using chloroform and ethyl acetate. Inhibition of fractions to the proliferation and differentiation of primary cultures of rat preadipocytes were tested to investigate the anti- adipogenic activity. Results: Separation of ethanol extract yielded three fractions, i.e. fraction of chloroform, fraction of ethyl acetate, and fraction of residual ethanol. The results of anti-proliferation and anti-differentiation activity test showed that the highest activity was demonstrated by ethyl acetate fraction, followed by residual ethanol fraction and chloroform fraction. The highest total flavonoid content was also shown by the fraction of ethyl acetate. Conclusion: The fraction of ethyl acetate showed the highest anti-adipogenic activity and the highest total flavonoid content

Paper Citation

in Harvard Style

Nuri., Prajogo B. and Sukardiman. (2018). Anti-Adipogenic Activity of Fractions of Guazuma ulmifolia Leaf.In Proceedings of BROMO Conference - Volume 1: BROMO, ISBN 978-989-758-347-6, pages 255-260. DOI: 10.5220/0008360902550260

in Bibtex Style

@conference{bromo18,
author={Nuri and Bambang Prajogo and Sukardiman},
title={Anti-Adipogenic Activity of Fractions of Guazuma ulmifolia Leaf},
booktitle={Proceedings of BROMO Conference - Volume 1: BROMO,},
year={2018},
pages={255-260},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008360902550260},
isbn={978-989-758-347-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of BROMO Conference - Volume 1: BROMO,
TI - Anti-Adipogenic Activity of Fractions of Guazuma ulmifolia Leaf
SN - 978-989-758-347-6
AU - Nuri.
AU - Prajogo B.
AU - Sukardiman.
PY - 2018
SP - 255
EP - 260
DO - 10.5220/0008360902550260