Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia

Septriyanto Dirgantara, Rosye H. R. Tanjung, Rahmawati Nurlatifah, Edy Meiyanto

Abstract

Background: Some medicinal plants from Papua which have been used traditionally as anticancer agents for many ethnic in Papua Islands. But, scientific evidence for this study were still limited. Objective: The present study was conducted to test for in vitro Brine Shrimp Lethality Test (BSLT) of the seven selected medicinal plants from Papua, namely, Drymis piperita (local name : Kayu Akway), Myrmecodia beccarii (Sarang semut), Biophytum petersianum (Rumput kebar), Vernonia amygdalina (Daun Afrika),Villebrunea rubescens( Daun Jilat), Laportea aestuans (Daun Gatal) and Breynia cernua (Katuk hutan). Methods: Seven ethanolic extracts were evaluated for their cytotoxic activity against Artemia salina Leach with concentration extracts from 10;100; and 1000 μg/mL. Cytotoxicity was evaluated in terms of LC 50 value from the 24 hour counts using the probit analysis method. Results: Ethanolic extracts of Myrmecodia beccarii showed the highest cytotoxicity with LC 50 was 8.33 μg/mL against brine shrimp, but all selected medicinal plants showed the active potential cytotoxic activity because the LC 50 value were <1000 μg/mL. Conclusion: From this research, M.beccarii indicated the possible potential use of medicinal plants from Papua as anticancer agents.

Paper Citation

in Harvard Style

Dirgantara S., Tanjung R., Nurlatifah R. and Meiyanto E. (2018). Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia.In Proceedings of BROMO Conference - Volume 1: BROMO, ISBN 978-989-758-347-6, pages 155-158. DOI: 10.5220/0008359001550158

in Bibtex Style

@conference{bromo18,
author={Septriyanto Dirgantara and Rosye H. R. Tanjung and Rahmawati Nurlatifah and Edy Meiyanto},
title={Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia},
booktitle={Proceedings of BROMO Conference - Volume 1: BROMO,},
year={2018},
pages={155-158},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008359001550158},
isbn={978-989-758-347-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of BROMO Conference - Volume 1: BROMO,
TI - Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia
SN - 978-989-758-347-6
AU - Dirgantara S.
AU - Tanjung R.
AU - Nurlatifah R.
AU - Meiyanto E.
PY - 2018
SP - 155
EP - 158
DO - 10.5220/0008359001550158