Nail Changes in Children Undergoing Chemotherapy

Ardelia Dyah Ayu, Reti Anggraeni, Endra Yustin Ellista Sari, Muh. Riza, Suci Widhiati

2018

Abstract

Many chemotherapeutic agents used in the management of various malignancies. Nail changes are often under recognized or attributed to other causes. The anticancer chemotherapeutic agents were known to cause a damage to the nail. This analytical, cross-sectional study was conducted in Dr. Moewardi General Hospital Surakarta between December 2017 and January 2018. The subjects were taken by consecutive sampling, consisting of 30 children undergoing chemotherapy and 30 healthy children as a control. History taking and physical examination in the form of digital photography as well as dermoscopic examination were conducted in all subjects. The data obtained were then analyzed using Mann-Whitney test, p < 0.05 was considered significant statistically. Nail changes were observed in 25/30 ( 83.3%) of the children receiving chemotherapy and they have a statistical significant difference compared to control group, with the p value 0.000. The nail changes obtained were trachonychia (22,2%), dyscromia (18.5%), melanonychia (14.8%), and Beau’s lines (14.8%). Combination of methotrexate and vincristine was the most frequent chemotherapeutic agent used in the subjects (40%). This study is expected to provide knowledge for dermatologist so that it can improve the promotive health, preventive, curative and education for the patient.

Paper Citation

in Harvard Style

Ayu A., Anggraeni R., Sari E., Riza M. and Widhiati S. (2018). Nail Changes in Children Undergoing Chemotherapy.In Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD, ISBN 978-989-758-494-7, pages 118-121. DOI: 10.5220/0008152101180121

in Bibtex Style

@conference{rcd18,
author={Ardelia Dyah Ayu and Reti Anggraeni and Endra Yustin Ellista Sari and Muh. Riza and Suci Widhiati},
title={Nail Changes in Children Undergoing Chemotherapy},
booktitle={Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,},
year={2018},
pages={118-121},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008152101180121},
isbn={978-989-758-494-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 23rd Regional Conference of Dermatology - Volume 1: RCD,
TI - Nail Changes in Children Undergoing Chemotherapy
SN - 978-989-758-494-7
AU - Ayu A.
AU - Anggraeni R.
AU - Sari E.
AU - Riza M.
AU - Widhiati S.
PY - 2018
SP - 118
EP - 121
DO - 10.5220/0008152101180121