Management for a Patient with Barret’s Esophagus: A Case Report

Muhammad Miftahussurur, Iswan Abbas Nusi, Poernomo Boedi Setiawan, Herry Purbayu, Titong Sugihartono, Ummi Maimunah, Ulfa Kholili, Budi Widodo, Husin Thamrin, Amie Vidyani

2017

Abstract

Barrett's esophagus (BE) is a displacement of the squamocolumnar border (SCJ) site to proximal to the gastroesophageal junction (GEJ) accompanied by the presence of intestinal metaplasia. BE develops when reflux-induced stomach acid destroys the squamous epithelial layer of the esophagus and this lesion heals via a metaplasia process in which the damaged squamous epithelial layer is replaced by columnar colon-type epithelium. BE prevalence in the general population is about 1.6-1.7%. Patients with gastroesophageal reflux disease (GERD) may progress to BE. This report concerns two cases of patients with Barrett's esophagus. In both these patients BE was found without dysplasia. A diagnosis was made on the basis of anamnesis, physical examination, laboratory, radiological, endoscopy and anatomical pathology. The management of BE is aimed at three main objectives: reduction of symptoms due to GERD, avoiding progression to strictures and ulcers, and preventing progression to adenocarcinoma. Both patients were given a PPI, a prokinetic and chemoprevention NSAID which achieved clinical improvement. Neither patient had ablation, photodynamic or mucosal resection. BE survival is much better than in groups without BE (5 years survival 61% vs. 28%, P = 0.001)

Paper Citation

in Harvard Style

Miftahussurur M., Nusi I., Setiawan P., Purbayu H., Sugihartono T., Maimunah U., Kholili U., Widodo B., Thamrin H. and Vidyani A. (2017). Management for a Patient with Barret’s Esophagus: A Case Report.In Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS, ISBN 978-989-758-340-7, pages 438-445. DOI: 10.5220/0007340304380445

in Bibtex Style

@conference{sips17,
author={Muhammad Miftahussurur and Iswan Abbas Nusi and Poernomo Boedi Setiawan and Herry Purbayu and Titong Sugihartono and Ummi Maimunah and Ulfa Kholili and Budi Widodo and Husin Thamrin and Amie Vidyani},
title={Management for a Patient with Barret’s Esophagus: A Case Report},
booktitle={Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,},
year={2017},
pages={438-445},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007340304380445},
isbn={978-989-758-340-7},
}

in EndNote Style

TY - CONF

JO - Proceedings of Surabaya International Physiology Seminar - Volume 1: SIPS,
TI - Management for a Patient with Barret’s Esophagus: A Case Report
SN - 978-989-758-340-7
AU - Miftahussurur M.
AU - Nusi I.
AU - Setiawan P.
AU - Purbayu H.
AU - Sugihartono T.
AU - Maimunah U.
AU - Kholili U.
AU - Widodo B.
AU - Thamrin H.
AU - Vidyani A.
PY - 2017
SP - 438
EP - 445
DO - 10.5220/0007340304380445