Tooth Mobility as an Impact of Psychological and Psycho-Physical Work Distress in a Rat Model

Zahreni Hamzah, Elyana Asnar, Suhartono Taat Putra

2017

Abstract

Tooth mobility is often found in workers with chronic work distress. Tooth mobility initially with the surrounding periodontal tissue destruction may be due to stress hormones. Periodontal tissue turnover capability is determined by the ability of differentiation of periodontal ligament stem cells/PDLSC into mature cells necessary for tissue formation. This study aimed to explain tooth mobility that is often found in workers with chronic work distress. This study used male Rattus norvegicus of Sprague-Dawley strain aged 3 months as the worker model. Methods. This was an experimental laboratory study using a Randomized Separate pretest-posttest control group design. The rats were grouped into four groups: Pre-test (P), post-test, consisting of control group (K), psychological distress (SP), and psycho-physical distress group (SPF), each consisting of eight rats. A stressor was provided with a home-made electric foot shock generator for 30 minutes every day in a communication box during 7 days. Examination of expression of Hsp-60, casp-3 and TGF-β in PDLSC was performed with IHC. Data was processed with multivariate analysis. Increased levels of corticosterone in the distressed condition increased the number of Hsp-60, Casp-3 and TGF-β expressing PDLSC. Increased expression of Hsp-60, Casp-3 and TGF-b in PDLSC in the psychological and psycho-physical work distressed condition may induce tooth mobility.

Paper Citation

in Harvard Style

Hamzah Z., Taat Putra S. and Asnar E. (2017). Tooth Mobility as an Impact of Psychological and Psycho-Physical Work Distress in a Rat Model.In Proceedings of the International Meeting on Regenerative Medicine - Volume 1: IMRM, ISBN 978-989-758-334-6, pages 212-217. DOI: 10.5220/0007319002120217

in Bibtex Style

@conference{imrm17,
author={Zahreni Hamzah and Suhartono Taat Putra and Elyana Asnar},
title={Tooth Mobility as an Impact of Psychological and Psycho-Physical Work Distress in a Rat Model},
booktitle={Proceedings of the International Meeting on Regenerative Medicine - Volume 1: IMRM,},
year={2017},
pages={212-217},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007319002120217},
isbn={978-989-758-334-6},
}

in EndNote Style

TY - CONF

JO - Proceedings of the International Meeting on Regenerative Medicine - Volume 1: IMRM,
TI - Tooth Mobility as an Impact of Psychological and Psycho-Physical Work Distress in a Rat Model
SN - 978-989-758-334-6
AU - Hamzah Z.
AU - Taat Putra S.
AU - Asnar E.
PY - 2017
SP - 212
EP - 217
DO - 10.5220/0007319002120217