Combination of 80% Trichloroacetic Acid Cross and Platelet-rich Fibrin Lysate for Improving Atrophic Acne Scar: A Case Series

Prima Meidiyanti, Dwi Retno Adiwinarni, Arief Budiyanto, Yohanes Widodo Wirohadidjojo

2019

Abstract

Atrophy scar is a major complication of acne vulgaris. Therapy for atrophicacne scar is a challenge for dermatologists. The technique of chemical reconstruction of skin scar (CROSS) by applying focal high concentrations of trichloroacetic acid (TCA) on the basis of an atrophic scar can stimulate collagen production. Platelet-Rich Fibrin (PRF) lysate is an immune concentrate and platelets that accumulate in one fibrin membrane which may be useful for atrophic acne scarby stimulating collagen deposition. Trichloroacetic acid and Lysate PRF work synergistically to improve atrophic acne scar. The purpose of this case report was to determine the effectiveness of a combination of 80% TCA CROSS and PRF lysate for atrophic acne scar to 2 patients of grade 3 and 4 in Goodman classification. Eighty percent TCA was applied on the basis of the atrophy scar using a wooden toothpick with a pointed tip and then PRF lysate applied to basis of scar every night. Digital photography analysis was performed in the next visit and found a significant improvement from the basis of atrophy in both patients with only onceTCA CROSS application. The combination of 80% TCA CROSS and PRF lysate are simple, easy to do, inexpensive procedures but provide excellent results for atrophic acne scar.

Paper Citation

in Harvard Style

Meidiyanti P., Adiwinarni D., Budiyanto A. and Wirohadidjojo Y. (2019). Combination of 80% Trichloroacetic Acid Cross and Platelet-rich Fibrin Lysate for Improving Atrophic Acne Scar: A Case Series.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 329-332. DOI: 10.5220/0009988003290332

in Bibtex Style

@conference{ictromi19,
author={Prima Meidiyanti and Dwi Retno Adiwinarni and Arief Budiyanto and Yohanes Widodo Wirohadidjojo},
title={Combination of 80% Trichloroacetic Acid Cross and Platelet-rich Fibrin Lysate for Improving Atrophic Acne Scar: A Case Series},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={329-332},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009988003290332},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Combination of 80% Trichloroacetic Acid Cross and Platelet-rich Fibrin Lysate for Improving Atrophic Acne Scar: A Case Series
SN - 978-989-758-469-5
AU - Meidiyanti P.
AU - Adiwinarni D.
AU - Budiyanto A.
AU - Wirohadidjojo Y.
PY - 2019
SP - 329
EP - 332
DO - 10.5220/0009988003290332