Comparison of C-Reactive Protein Levels and Erythrocyte Sedimentation Rates to Osteoarthritis Patients with Sidaguri Extract Treatment within 1 Month and 2 Month

Blondina Marpaung, J. Siregar

2019

Abstract

Osteoarthritis (OA) is defined as a heterogeneous condition that leads to joint sign and symptoms caused by defective integrity of articular cartilage and inflammation. CRP is a sensitive acute phase reactant with levels rapidly rising in many inflammation conditions. ESR is an indirect measure of the level of inflammation in the body. The management of OA limited in the pain and inflammation control with any NSAID. Meloxicam is one of NSAID that inhibits the synthesis of prostaglandins by inhibiting at least 2 cyclo-oxygenases (COX) isoenzymes. Sidaguri plant (Sida rhombifolia L.) is one of the most important species of the medicinal part in Indonesia as anti-inflammation, by inhibition of nitric oxide and protein denaturation inhibitions. Our study recruited 50 patients with OA divided into two groups, patients who get Meloxicam and Sidaguri (n = 25) and patients with Meloxicam and placebo (n = 25). There were significant differences before, one month, and two months after therapy with p-value <0.001, and the Sidaguri combination with meloxicam is better in reducing CRP and ESR levels.

Paper Citation

in Harvard Style

Marpaung B. and Siregar J. (2019). Comparison of C-Reactive Protein Levels and Erythrocyte Sedimentation Rates to Osteoarthritis Patients with Sidaguri Extract Treatment within 1 Month and 2 Month.In Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI, ISBN 978-989-758-469-5, pages 33-37. DOI: 10.5220/0009855600330037

in Bibtex Style

@conference{ictromi19,
author={Blondina Marpaung and J. Siregar},
title={Comparison of C-Reactive Protein Levels and Erythrocyte Sedimentation Rates to Osteoarthritis Patients with Sidaguri Extract Treatment within 1 Month and 2 Month},
booktitle={Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,},
year={2019},
pages={33-37},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0009855600330037},
isbn={978-989-758-469-5},
}

in EndNote Style

TY - CONF

JO - Proceedings of the 2nd International Conference on Tropical Medicine and Infectious Disease - Volume 1: ICTROMI,
TI - Comparison of C-Reactive Protein Levels and Erythrocyte Sedimentation Rates to Osteoarthritis Patients with Sidaguri Extract Treatment within 1 Month and 2 Month
SN - 978-989-758-469-5
AU - Marpaung B.
AU - Siregar J.
PY - 2019
SP - 33
EP - 37
DO - 10.5220/0009855600330037