Design of a Breath Analysis Device for Self-monitoring and Remote Health-care

D. Germanese, M. D'Acunto, O. Salvetti

Abstract

Technique as new as promising, breath analysis enables the monitoring of biochemical processes in human body in a non-invasive way. This is why it is drawing, more and more, the attention of scientific community: many studies have been addressed in order to find a correlation between breath volatile organic compounds (VOCs) and several diseases. Despite its potential, breath analysis is still far from being used in clinical practice. These are some of the principal reasons: (i)high costs for the standard analytical instrumentation; (ii)need of specialized personnel for the interpretation of the results; (iii)lack of standardized procedures to collect breath samples. Our aim is to develop a device, which we call Wize Sniffer (WS), based on commercial gas sensors, which is: (i)able to analyse breath gases in real time; (ii)portable; (iii)low-cost; (iv)easy-to-use also for non-specialized personnel. Another aim is to foster homecare, that means promote the purchase and the use, also in home environment, of such device. The Wize Sniffer is composed of three modules: signal measurement, signal conditioning and signal processing. To satisfy the goal of developing a device by using low-cost technology, its core is composed of an array of commercial, low cost, semiconductor-based gas sensors, and a widely employed open source controller: an Arduino board. To promote the use of such device also in home environment, and foster its daily use, it is programmed in order to send breath test results also to a remote pc: the pc of user’s physician, for example. In addition, the design of the Wize Sniffer is based on a modular configuration, thus enabling to change the type of the gas sensors according to the breath molecules to be detected. In this case, we focus our attention to the prevention of cardio-metabolic risk, for which the healthcare systems are registering an exponential growth of social costs, by monitoring those dangerous habits for cardio-metabolic risk itself.

References

  1. Anthonisen N. R., Robertson P. C. and Ross W. R., 1970. Gravity-dependent sequential emptying of lung regions. In J. Appl. Physiol., 589-95.
  2. Di Francesco F., Fuoco R., Trivella M., Ceccarini A., 2005. Breath Analysis: trends in techniques and clinical applications. In Microchemical Journal, vol.79, no 1-2, pp.405-410.
  3. Di Francesco F., Loccioni C., Fioravanti M., Russo A., Pioggia G., Ferro M., Roehrer I., Tabucchi S., Onor M., 2008. Implementation of Fowler's method for end-tidal air sampling. In Journal of Breath Research.
  4. Ding B., Wang M., Yu J., Sun G., 2009. Gas sensors based on electrospun nanofibers. In Sensors 2009.
  5. Guo D., Zhang D., Li N., Zhang L., Yang J., 2010. A novel breath analysis system based on electronic olfaction. In IEEE Transaction on Biomedical Engineering.
  6. Jones J.G.., 1967. The effect of pre-inspiratory lung volumes on the result of the single breath O2 test. In Respiratory Physiology, 375-85.
  7. Jones J.G., Clarke S.W., 1969. Effect of expiratory flow rate on regional lung emptying. In Clin. Sci. 343-56.
  8. Miekisch W., Kischkel S., Sawacki A., Lieban T., Mieth M., Schubert J.K., 2008. Impact of sampling procedures on the result of breath analysis. In Journal of Breath Research.
  9. Miekisch W., Schubert J.K., Noeldge-Schomburg G.F.E., 2004. Diagnostic potential of breath analysis- focus on volatile organic compounds. In Clinica Chimica Acta, 347, pp.25-39.
  10. Pabst F., Miekisch W., Fuchs P., Kischkel S., Schubert J.K., 2005. Monitoring of oxidative and metabolic stress during cardiac surgery by means of breath biomarkers: an observational study. In Journal of Cardiothoracic Surgery, 2:37.
  11. Phillips M., Cataneo R. N., Greenberg J., Grodman R., Salasar M., 2003. Breath Markers in oxidative stress in patients with unstable angina. In Heart Disease, vol.5.
  12. Risby T.H. and Solga S.F., 2006. Current status of clinical breath analysis. In Applied Physics B 85, pp.421-426.
  13. Shier D., Butler J., Lewis R., 2007. Hole's Human Anatomy & Physiology . 11th Ed., McGraw-Hill.
Download


Paper Citation


in Harvard Style

Germanese D., D'Acunto M. and Salvetti O. (2016). Design of a Breath Analysis Device for Self-monitoring and Remote Health-care . In Doctoral Consortium - DCBIOSTEC, ISBN , pages 9-14


in Bibtex Style

@conference{dcbiostec16,
author={D. Germanese and M. D'Acunto and O. Salvetti},
title={Design of a Breath Analysis Device for Self-monitoring and Remote Health-care},
booktitle={Doctoral Consortium - DCBIOSTEC,},
year={2016},
pages={9-14},
publisher={SciTePress},
organization={INSTICC},
doi={},
isbn={},
}


in EndNote Style

TY - CONF
JO - Doctoral Consortium - DCBIOSTEC,
TI - Design of a Breath Analysis Device for Self-monitoring and Remote Health-care
SN -
AU - Germanese D.
AU - D'Acunto M.
AU - Salvetti O.
PY - 2016
SP - 9
EP - 14
DO -