Denoising 3D Microscopy Images of Cell Nuclei using Shape Priors on an Anisotropic Grid

Mathieu Bouyrie, Cristina Manfredotti, Nadine Peyriéras, Antoine Cornuéjols

Abstract

This paper presents a new multiscale method to denoise three-dimensional images of cell nuclei. The specificity of this method is its awareness of the noise distribution and object shapes. It combines a multiscale representation called Isotropic Undecimated Wavelet Transform (IUWT) with a nonlinear transform, a statistical test and a variational method, to retrieve spherical shapes in the image. Beyond extending an existing 2D approach to a 3D problem, our algorithm takes the sampling grid dimensions into account. We compare our method to the two algorithms from which it is derived on a representative image analysis task, and show that it is superior to both of them. It brings a slight improvement in the signal-to-noise ratio and a significant improvement in cell detection.

References

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Paper Citation


in Harvard Style

Bouyrie M., Manfredotti C., Peyriéras N. and Cornuéjols A. (2016). Denoising 3D Microscopy Images of Cell Nuclei using Shape Priors on an Anisotropic Grid . In Proceedings of the 5th International Conference on Pattern Recognition Applications and Methods - Volume 1: ICPRAM, ISBN 978-989-758-173-1, pages 291-298. DOI: 10.5220/0005706002910298


in Bibtex Style

@conference{icpram16,
author={Mathieu Bouyrie and Cristina Manfredotti and Nadine Peyriéras and Antoine Cornuéjols},
title={Denoising 3D Microscopy Images of Cell Nuclei using Shape Priors on an Anisotropic Grid},
booktitle={Proceedings of the 5th International Conference on Pattern Recognition Applications and Methods - Volume 1: ICPRAM,},
year={2016},
pages={291-298},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005706002910298},
isbn={978-989-758-173-1},
}


in EndNote Style

TY - CONF
JO - Proceedings of the 5th International Conference on Pattern Recognition Applications and Methods - Volume 1: ICPRAM,
TI - Denoising 3D Microscopy Images of Cell Nuclei using Shape Priors on an Anisotropic Grid
SN - 978-989-758-173-1
AU - Bouyrie M.
AU - Manfredotti C.
AU - Peyriéras N.
AU - Cornuéjols A.
PY - 2016
SP - 291
EP - 298
DO - 10.5220/0005706002910298