A Flexible PET-based Wearable Sensor for Arterial Pulse Waveform Measurement

Dan Wang, Dean Krusienski, Zhili Hao


In light of the need of health monitoring, the paper presents a flexible polyethylene terephthalate (PET)-based wearable sensor for arterial pulse waveform measurement. The sensor encompasses a polydimethylsiloxane (PDMS) microstructure embedded with an electrolyte-enabled 5×1 transducer array, which spans 6mm and has a spatial resolution of 1.5mm. A pulse signal exerts a deflection on the microstructure and is recorded as a resistance change by a transducer at the site of the pulse. An untrained individual can easily align the sensor on a targeted artery with a negligible margin and then acquire the arterial pulse waveform continuously and non-invasively. This sensor is fabricated using microfluidics technology and thus features low cost for mass production. The sensor is hand-held on an artery and records its pulse signal for a 10s period, which bears baseline drift, due to the respiration and the motion artifact. Discrete Meyer Wavelet Transform (DMWT) and Cubic Spline Estimation (CSE) are employed to remove baseline drift in a pulse signal. The pulse waveform is expressed in terms of the sensor deflection as a function of time. Carotid arterial pulse waveforms are measured by the sensor on three subjects at rest and on two subjects post-exercise. Additionally, radial arterial waveforms are measured on one subject at rest. The measured pulse pattern change of the two subjects between at rest and post-exercise is consistent with the literature. As the pulse transmits from central (carotid) to peripheral (radial) for one subject, the ratio of amplitude of main peak to amplitude of dicrotic wave goes up and the up-stroke time becomes shorter. This is consistent with the related observations in the literature. Thus, the limited amount of data collected here demonstrates the feasibility of using the sensor as a wearable health monitoring device.


  1. Cheng, P., Gu, W., Shen, J., Ghosh, A., Beskok, A. and Hao, Z., 2013. Performance study of a PDMS-based microfluidic device for the detection of continuous distributed static and dynamic loads. Journal of Micromechanics and Microengineering, 23(8), p. 085007.
  2. Digiglio, P., Li, R., Wang, W. and Pan, T., 2014. Microflotronic arterial tonometry for continuous wearable non-invasive hemodynamic monitoring. Annals of biomedical engineering, 42(11), pp.2278- 2288.
  3. Gu, W., Cheng, P., Ghosh, A., Liao, Y., Liao, B., Beskok, A. and Hao, Z., 2013. Detection of distributed static and dynamic loads with electrolyte-enabled distributed transducers in a polymer-based microfluidic device. Journal of Micromechanics and Microengineering, 23(3), p.035015.
  4. Hu, C. S., Chung, Y. F., Yeh, C. C., and Luo, C. H., 2011. Temporal and spatial properties of arterial pulsation measurement using pressure sensor array. EvidenceBased Complementary and Alternative Medicine, 2012.
  5. Hurst, J. W. and Logue, R. B., 1982. The heart: arteries and veins, McGraw -Hill, pp.170-179.
  6. Lin, W. H., Zhang, H. and Zhang, Y. T., 2013. Investigation on cardiovascular risk prediction using physiological parameters. Computational and mathematical methods in medicine, 2013.
  7. McEniery, C. M., Cockcroft, J. R., Roman, M. J., Franklin, S. S. and Wilkinson, I. B., 2014. Central blood pressure: current evidence and clinical importance. European heart journal, 35(26), pp.1719- 1725.
  8. O'Rourke, M. F. and Hashimoto, J., 2007. Mechanical factors in arterial aging: a clinical perspective. Journal of the American College of Cardiology, 50(1), pp.1-13.
  9. Saugel, B., Fassio, F., Hapfelmeier, A., Meidert, A. S., Schmid, R. M., and Huber, W., 2012. The T-Line TL200 system for continuous non-invasive blood pressure measurement in medical intensive care unit patients. Intensive care medicine. 38(9), pp.1471-1477.
  10. Studinger, P., Lenard, Z., Kovats, Z., Kocsis, L. and Kollai, M., 2003. Static and dynamic changes in carotid artery diameter in humans during and after strenuous exercise. The Journal of physiology, 550(2), pp.575-583.
  11. Tang, L. and Lee, N. Y., 2010. A facile route for irreversible bonding of plastic-PDMS hybrid microdevices at room temperature. Lab on a Chip, 10(10), pp.1274-1280.
  12. Tsuwaki, M., Kasahara, T., Edura, T., Matsunami, S., Oshima, J., Shoji, S., Adachi, C. and Mizuno, J., 2014. Fabrication and characterization of large-area flexible microfluidic organic light-emitting diode with liquid organic semiconductor. Sensors and Actuators A: Physical, 216, pp.231-236.
  13. Velik, R., 2015. An objective review of the technological developments for radial pulse diagnosis in Traditional Chinese Medicine. European Journal of Integrative Medicine, 7(4), pp.321-331.
  14. Xu, L., Zhang, D., Wang, K., Li, N. and Wang, X., 2007. Baseline wander correction in pulse waveforms using wavelet-based cascaded adaptive filter. Computers in Biology and Medicine, 37(5), pp. 716-731.
  15. Yang, Y., Shen, J. and Hao, Z., 2015. A two-demensional (2D) distributed deflection sensor for tissue palpation with correction mechanism for its performance variation. under review.

Paper Citation

in Harvard Style

Wang D., Krusienski D. and Hao Z. (2016). A Flexible PET-based Wearable Sensor for Arterial Pulse Waveform Measurement . In Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2016) ISBN 978-989-758-170-0, pages 66-75. DOI: 10.5220/0005698000660075

in Bibtex Style

author={Dan Wang and Dean Krusienski and Zhili Hao},
title={A Flexible PET-based Wearable Sensor for Arterial Pulse Waveform Measurement},
booktitle={Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2016)},

in EndNote Style

JO - Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2016)
TI - A Flexible PET-based Wearable Sensor for Arterial Pulse Waveform Measurement
SN - 978-989-758-170-0
AU - Wang D.
AU - Krusienski D.
AU - Hao Z.
PY - 2016
SP - 66
EP - 75
DO - 10.5220/0005698000660075