Temporally Synchronized Reversible Data Hiding of EEG to MREG

Angelos Fylakis, Anja Keskinarkaus, Vesa Kiviniemi, Tapio Seppänen


Simultaneous MREG and EEG recordings are vastly used in neurobiology, but so far they are stored and handled as separate files. This paper proposes a method to combine those two entities with the objective of establishing data management efficiency, while secondary objectives are confidentiality, availability and reliability in data. To be more specific, it is a reversible data hiding method for hiding EEG in MREG with the ability of fully recovering MREG and the embedded EEG signal. It is based on histogram shifting, exploiting data quantization and Region of Interest segmentation. The embedding procedure maintains temporal synchronization between EEG and 32-bit MREG making it a novel data hiding application. It is demonstrated through experiments that MREG maintains high perceptual fidelity and also verified that after EEG extraction and acquisition of every electrode’s sample, MREG is fully reversed to its exact initial state.


  1. Collberg, C., and Nagra, J., 2010. Surreptitious software. Addison-Wesley, Upper Saddle River, NJ, 1st edition.
  2. Coatrieux, G., Lecornu, L., Sankur, B., and Roux, C., 2006. A review of image watermarking applications in healthcare, In Engineering in Medicine and Biology Society, 28th Annual International Conference of the IEEE, pages 4691-4694.
  3. Cox, I., Miller, M., Bloom, J., Fridrich, J., and Kalker, T., 2007. Digital watermarking and steganography. Morgan Kaufmann. Burlington, MA, 2nd edition.
  4. Czisch, M., Wehrle, R., Kaufmann, C., Wetter, T. C., Holsboer, F., Pollmacher, T., and Auer, D. P., 2004. Functional MRI during sleep: BOLD signal decreases and their electrophysiological correlates. In European Journal of Neuroscience, volume 20, pages 566-574.
  5. Dharwadkar, N. V., Amberker, B., Panchannavar, S., and Panchannavar, P., 2010. Reversible fragile medical image watermarking with zero distortion. In Int'l Conference in Computer and Communication Technology, IEEE, pages 248-254.
  6. Fallahpour, M., Megias, D., and Ghanbari, M., 2011. Reversible and highcapacity data hiding in medical images. In IET Image Processing, 5(2):190-197.
  7. Goldberger, A. L., Amaral, L. A., Glass, L., Hausdorff, J. M., Ivanov, P. C., Mark, R. G., Mietus, J. E., Moody G. B., Peng C. K., and Stanley, H. E., 2000. Physiobank, physiotoolkit, and physionet components of a new research resource for complex physiologic signals. In Circulation, 101(23):215-220.
  8. Gonzalez, R. C., Woods, R. E., 2002. Digital image processing, Prentice-Hall. Upper Saddle River, NJ, 3rd edition.
  9. Grover, D., 1997. The protection of computer software - its technology and applications, Cambridge University Press. NY.
  10. Jacobs, J., Stich, J., Zahneisen, B., Assländer, J., Ramantani, G., Schulze-Bonhage A., Korinthenberg, R., Hennig, J., and LeVan, P., 2014. Fast fMRI provides high statistical power in the analysis of epileptic networks. in Neuroimage, volume 88, pages 282-294.
  11. Jenkinson, M., Pechaud, M., and Smith. S., 2005. BET2: MR-based estimation of brain, skull and scalp surfaces. In Eleventh Annual Meeting of the Organization for Human Brain Mapping, volume 17.
  12. Makeig, S., Westerfield, M., Jung, T. P., Enghoff, S., Townsend, J., Courchesne, E., and Sejnowski, T. J., 2002. Dynamic brain sources of visual evoked responses. In Science, volume 295, pages 690-694.
  13. Menon, V., and Crottaz-Herbette, S., 2005. Combined EEG and fMRI studies of human brain function. In International Review of Neurobiology, volume 66, pages 291-321.
  14. National Institute of Standards and Technology, 2014. Descriptions of SHA-256, SHA-384, and SHA-512. csrc.nist.gov/groups/STM/cavp/documents/shs/sha256 -384-512.pdf.
  15. Ni, Z., Shi, Y. Q., Ansari, N. and Shu, W., 2006. Reversible data hiding. In IEEE Transactions on Circuits and Systems for Video Technology, 16(3):354-362.
  16. Pan, W., Coatrieux, G., Montagner, J., Cuppens, N., Cuppens, F., and Roux, C., 2009. Comparison of some reversible watermarking methods in application to medical images, In 31st Annual International IEEE Conference on Engineering in Medicine and Biology Society, pages 2172-2175.
  17. Rajna, Z., Kananen, J., Keskinarkaus, A., Seppänen, T., and Kiviniemi, V., 2015. Detection of short-term activity avalanches in human brain default mode network with ultrafast MR encephalography, In Frontiers in Human Neuroscience, 9(448).
  18. Ruzzo, A., 2014. Biobanking's big problem: how do you manage all that data? blog.fisherbioservices.com/bid /376102/Biobanking-s-Big-Problem-How-do-youmanage-all-that-data.
  19. Sriraam, N., 2012. A high-performance lossless compression scheme for EEG signals using wavelet transform and neural network predictors. In International Journal of Telemedicine and Applications, 2012(5): 1-8.
  20. Tsai, P., Hu, Y. C., and Yeh, H. L., 2009. Reversible image hiding scheme using predictive coding and histogram shifting. In Signal Processing, 89(6):1129- 1143.
  21. Wongsawat, Y., Oraintara, S., and Rao, K. R., 2006. Integer sub-optimal Karhunen-Loeve transform for multichannel lossless EEG compression. In 14th European Signal Processing Conference, IEEE, pages 1-6.

Paper Citation

in Harvard Style

Fylakis A., Keskinarkaus A., Kiviniemi V. and Seppänen T. (2016). Temporally Synchronized Reversible Data Hiding of EEG to MREG . In Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF, (BIOSTEC 2016) ISBN 978-989-758-170-0, pages 58-67. DOI: 10.5220/0005665700580067

in Bibtex Style

author={Angelos Fylakis and Anja Keskinarkaus and Vesa Kiviniemi and Tapio Seppänen},
title={Temporally Synchronized Reversible Data Hiding of EEG to MREG},
booktitle={Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF, (BIOSTEC 2016)},

in EndNote Style

JO - Proceedings of the 9th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF, (BIOSTEC 2016)
TI - Temporally Synchronized Reversible Data Hiding of EEG to MREG
SN - 978-989-758-170-0
AU - Fylakis A.
AU - Keskinarkaus A.
AU - Kiviniemi V.
AU - Seppänen T.
PY - 2016
SP - 58
EP - 67
DO - 10.5220/0005665700580067