POSITIONING AND ORIENTATION OF ADHERENT CELLS IN A MICROFLUIDIC CHIP USING THE MICRO PATTERNING OF A PARYLENE-C FILM

Claire Dalmay, Jun-Jung Lai, Laurent Griscom, Olivier Français, Bruno Le Pioufle, Frédéric Subra, Patrick Tauc, Joseph Lautru

Abstract

A new method for the positioning and orientation of adherent cells on a culture substrate is presented. We demonstrate the ability of a micro patterned parylene-C film deposited on a fused silica substrate to position, isolate and/or orientate cells. Such features are crucial for the development of future biodevices for the analysis and treatment of single-cell or organized cell tissues. In particular, our method is advantageous for controlling the orientation of the cells within an organized tissue while being exposed to an electrical field. The developed method does not require any chemical treatment of the cells or any additional surface modification and is suitable for integration into a microfluidic system.

References

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Paper Citation


in Harvard Style

Dalmay C., Lai J., Griscom L., Français O., Le Pioufle B., Subra F., Tauc P. and Lautru J. (2011). POSITIONING AND ORIENTATION OF ADHERENT CELLS IN A MICROFLUIDIC CHIP USING THE MICRO PATTERNING OF A PARYLENE-C FILM . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011) ISBN 978-989-8425-37-9, pages 212-215. DOI: 10.5220/0003156702120215


in Bibtex Style

@conference{biodevices11,
author={Claire Dalmay and Jun-Jung Lai and Laurent Griscom and Olivier Français and Bruno Le Pioufle and Frédéric Subra and Patrick Tauc and Joseph Lautru},
title={POSITIONING AND ORIENTATION OF ADHERENT CELLS IN A MICROFLUIDIC CHIP USING THE MICRO PATTERNING OF A PARYLENE-C FILM},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011)},
year={2011},
pages={212-215},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003156702120215},
isbn={978-989-8425-37-9},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2011)
TI - POSITIONING AND ORIENTATION OF ADHERENT CELLS IN A MICROFLUIDIC CHIP USING THE MICRO PATTERNING OF A PARYLENE-C FILM
SN - 978-989-8425-37-9
AU - Dalmay C.
AU - Lai J.
AU - Griscom L.
AU - Français O.
AU - Le Pioufle B.
AU - Subra F.
AU - Tauc P.
AU - Lautru J.
PY - 2011
SP - 212
EP - 215
DO - 10.5220/0003156702120215