FUNCTIONAL STATUS AND THE EYE-TRACKING RESPONSE - A Data Mining Classification Study in the Vegetative and Minimaly Conscious States

A. Candelieri, F. Riganello, D. Cortese, W. G. Sannita

Abstract

Eye-tracking is defined as the “pursuit eye movement or sustained fixation that occurs in direct response to moving or salient stimuli”; it is a key descriptor of the evolution from the vegetative (VS) to the minimally conscious (MCS) state and predicts better outcome. In this study, several physiological parameters (such as heart beat, Galvanic Skin Response [GSR], Blood Volume Pulse [BVP], respiratory rate and amplitude) were recorded while a medical examiner searched for eye-tracking by slowly moving a visual stimulus horizontally and vertically in front of the subject. Seven patients in VS and 8 in MCS were studied. The Heart Rate Variability (HRV) was analyzed to obtain time and frequency descriptors. Different classification methods were adopted to search for a plausible relationship between the subject psycho-physiological state and observable eye-tracking to stimuli. The performance of different classifiers was computed as Balanced Classification Accuracy (BCA) and evaluated through suitable validation technique. A Support Vector Machine (SVM) classifier provided the most reliable relationship: BCA mean was about 84% on fold cross validation and about 75% on an independent test set of 6 patients (3 VS and 3 MCS).

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in Harvard Style

Candelieri A., Riganello F., Cortese D. and G. Sannita W. (2011). FUNCTIONAL STATUS AND THE EYE-TRACKING RESPONSE - A Data Mining Classification Study in the Vegetative and Minimaly Conscious States . In Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2011) ISBN 978-989-8425-34-8, pages 138-141. DOI: 10.5220/0003128201380141


in Bibtex Style

@conference{healthinf11,
author={A. Candelieri and F. Riganello and D. Cortese and W. G. Sannita},
title={FUNCTIONAL STATUS AND THE EYE-TRACKING RESPONSE - A Data Mining Classification Study in the Vegetative and Minimaly Conscious States},
booktitle={Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2011)},
year={2011},
pages={138-141},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003128201380141},
isbn={978-989-8425-34-8},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Health Informatics - Volume 1: HEALTHINF, (BIOSTEC 2011)
TI - FUNCTIONAL STATUS AND THE EYE-TRACKING RESPONSE - A Data Mining Classification Study in the Vegetative and Minimaly Conscious States
SN - 978-989-8425-34-8
AU - Candelieri A.
AU - Riganello F.
AU - Cortese D.
AU - G. Sannita W.
PY - 2011
SP - 138
EP - 141
DO - 10.5220/0003128201380141