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Depto. de Ingeniería Mecánica, Energética y de los Materiales and Instituto de Computación Científica Avanzada, Universidad de Extremadura, Badajoz, Spain

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1 Papers

In Vitro Flow Study in an Intracranial Aneurysm Biomodel Manufactured by Additive Manufacturing

Topic: Lab on a Chip and Microfluidic Devices

Authors: Andrews Souza ^{1

;

2

;

3} , Diana Rodrigues ¹ , Maria Souza ⁴ , Conrado Ferrera ⁵ , João Ribeiro ^{3

;

4} , Rui A. Lima ^{1

;

2} and Ana Moita ^{6

;

7}

Affiliations: ¹ University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal , ² Mechanical Engineering and Resource Sustainability Center (MEtRICs), UMinho, Guimarães, Portugal , ³ Centro de Investigação de Montanha (CIMO), Instituto Politécnico de Bragança (IPB), Campus de Santa Apolónia, 5300-253 Bragança, Portugal , ⁴ Instituto Politécnico de Bragança, 5300-253, Bragança, Portugal , ⁵ Depto. de Ingeniería Mecánica, Energética y de los Materiales and Instituto de Computación Científica Avanzada, Universidad de Extremadura, Badajoz, Spain , ⁶ IN+, Center for Innovation, Technology and Policy Research, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal , ⁷ CINAMIL, Department of Exact Sciences and Engineering, Portuguese Military Academy, R. Gomes Freire 203, 1169-203 Lisboa, Portugal

Digital Object Identifier: 10.5220/0011652100003414

Proceedings of BIODEVICES 2023/BIOSTEC, ISBN: 978-989-758-631-6

Quick Abstract

The hemodynamics of Intracranial Aneurysm (IA) involves complex phenomena that influence its growth and rupture. The progress of additive manufacturing techniques has allowed the development of biomodels suitable to perform in vitro flow experiments. Hence, this work presents the manufacturing process to fabricate flow biomodels by using the additive manufacturing technique known as Fused Deposition Modeling (FDM). The biomodels obtained through the proposed technique has proved to be suitable for in vitro flow experiments using imaging techniques and for validation of numerical studies.