Optical Technology for Fibrotic Skin Changes Objectification in Experimental Systemic Scleroderma

Yulia Chursinova, Dmitriy Kulikov, Dmitry Rogatkin, Irina Raznitsyna, Darya Mosalskaya, Maksim Bobrov

Abstract

Currently the examination of skin fibrosis is based on subjective non quantitative methods and requires invasive procedures. Optical techniques abled to evaluate different quantitative parameters of ordered tissues can be used to solve these problem. Measurements of endogenous fluorescence intensity, regional tissue oxyhemoglobin saturation, and blood filling volume allowed to define the high endogenous fluorescence intensity of porphyrin in skin fibrosis. Besides that, the decrease in oxygen intake parameters together with the fluorescence intensity increase of collagen was determined. Consequently the optical diagnostic techniques can become an effective method for skin fibrosis evaluation.

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Paper Citation


in Harvard Style

Chursinova Y., Kulikov D., Rogatkin D., Raznitsyna I., Mosalskaya D. and Bobrov M. (2018). Optical Technology for Fibrotic Skin Changes Objectification in Experimental Systemic Scleroderma.In Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, ISBN 978-989-758-277-6, pages 194-199. DOI: 10.5220/0006633101940199


in Bibtex Style

@conference{biodevices18,
author={Yulia Chursinova and Dmitriy Kulikov and Dmitry Rogatkin and Irina Raznitsyna and Darya Mosalskaya and Maksim Bobrov},
title={Optical Technology for Fibrotic Skin Changes Objectification in Experimental Systemic Scleroderma},
booktitle={Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,},
year={2018},
pages={194-199},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006633101940199},
isbn={978-989-758-277-6},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 11th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES,
TI - Optical Technology for Fibrotic Skin Changes Objectification in Experimental Systemic Scleroderma
SN - 978-989-758-277-6
AU - Chursinova Y.
AU - Kulikov D.
AU - Rogatkin D.
AU - Raznitsyna I.
AU - Mosalskaya D.
AU - Bobrov M.
PY - 2018
SP - 194
EP - 199
DO - 10.5220/0006633101940199