Identifying Isolated Glioblastoma Tissues in Human Patients through Their Optical and Spectral Properties

Hussein Mehidine, Fanny Poulon, Ali Ibrahim, Marjorie Juchaux, Pascale Varlet, Bertrand Devaux, Johan Pallud, Darine Abi Haidar

Abstract

Survival rates and health-related quality of life of adult patients suffering from glioblastoma depend significantly on the extent (no residual tumor tissue) and precision (no collateral damage) of the surgical resection. Assistance in defining the borders of the infiltrating component of the glioblastoma would be valuable to improve outcomes. A tissue can be defined by its optical properties : absorption, scattering, intensity of fluorescence, that will give a unique signature. In this work we look at the absorption and scattering coefficients of glioblastoma and control tissues from adult patients using an integrating sphere, spectral measurements were also took on the samples using a fiber endoscope. The preliminary results show the potential of using endogenous fluorescence for intraoperative identification of residual glioblastoma tissue in the wall of the surgical cavity of resection.

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Paper Citation


in Harvard Style

Mehidine H., Poulon F., Ibrahim A., Juchaux M., Varlet P., Devaux B., Pallud J. and Abi Haidar D. (2018). Identifying Isolated Glioblastoma Tissues in Human Patients through Their Optical and Spectral Properties.In Proceedings of the 6th International Conference on Photonics, Optics and Laser Technology - Volume 1: PHOTOPTICS, ISBN 978-989-758-286-8, pages 136-140. DOI: 10.5220/0006531501360140


in Bibtex Style

@conference{photoptics18,
author={Hussein Mehidine and Fanny Poulon and Ali Ibrahim and Marjorie Juchaux and Pascale Varlet and Bertrand Devaux and Johan Pallud and Darine Abi Haidar},
title={Identifying Isolated Glioblastoma Tissues in Human Patients through Their Optical and Spectral Properties},
booktitle={Proceedings of the 6th International Conference on Photonics, Optics and Laser Technology - Volume 1: PHOTOPTICS,},
year={2018},
pages={136-140},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006531501360140},
isbn={978-989-758-286-8},
}


in EndNote Style

TY - CONF

JO - Proceedings of the 6th International Conference on Photonics, Optics and Laser Technology - Volume 1: PHOTOPTICS,
TI - Identifying Isolated Glioblastoma Tissues in Human Patients through Their Optical and Spectral Properties
SN - 978-989-758-286-8
AU - Mehidine H.
AU - Poulon F.
AU - Ibrahim A.
AU - Juchaux M.
AU - Varlet P.
AU - Devaux B.
AU - Pallud J.
AU - Abi Haidar D.
PY - 2018
SP - 136
EP - 140
DO - 10.5220/0006531501360140