Endogenous Fluorescence Analysis under Deep UV Excitation to Discriminate Human Brain Tumor Tissue - Difference between Glioblastoma and Healthy Control Tissue

F. Poulon, F. Jamme, A. Ibrahim, C. Métais, P. Varlet, M. Juchaux, B. Devaux, M. Refregiers, D. Abi Haidar

Abstract

In order to build a multimodal nonlinear endomicroscope to image brain border during operation, our group is building an optical database on brain biopsy tissues analysis collected with excitation panning from deep UV to near infrared. This paper focuses on the results from deep UV excitation of endogenous fluorescence from glioblastoma and control human brain samples. The samples were imaged and spectrally analysed. The excitation wavelengths were tuned from 275 nm to 340 nm. Two promising indicators to discriminate tumorous tissue from the control were found. A preliminary correspondence between fluorescence images and histological H&E staining open a huge door to confirm results with a medical expertise.

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Paper Citation


in Harvard Style

Poulon F., Jamme F., Ibrahim A., Métais C., Varlet P., Juchaux M., Devaux B., Refregiers M. and Abi Haidar D. (2017). Endogenous Fluorescence Analysis under Deep UV Excitation to Discriminate Human Brain Tumor Tissue - Difference between Glioblastoma and Healthy Control Tissue . In Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology - Volume 1: PHOTOPTICS, ISBN 978-989-758-223-3, pages 152-157. DOI: 10.5220/0006103601520157


in Bibtex Style

@conference{photoptics17,
author={F. Poulon and F. Jamme and A. Ibrahim and C. Métais and P. Varlet and M. Juchaux and B. Devaux and M. Refregiers and D. Abi Haidar},
title={Endogenous Fluorescence Analysis under Deep UV Excitation to Discriminate Human Brain Tumor Tissue - Difference between Glioblastoma and Healthy Control Tissue},
booktitle={Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology - Volume 1: PHOTOPTICS,},
year={2017},
pages={152-157},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006103601520157},
isbn={978-989-758-223-3},
}


in EndNote Style

TY - CONF
JO - Proceedings of the 5th International Conference on Photonics, Optics and Laser Technology - Volume 1: PHOTOPTICS,
TI - Endogenous Fluorescence Analysis under Deep UV Excitation to Discriminate Human Brain Tumor Tissue - Difference between Glioblastoma and Healthy Control Tissue
SN - 978-989-758-223-3
AU - Poulon F.
AU - Jamme F.
AU - Ibrahim A.
AU - Métais C.
AU - Varlet P.
AU - Juchaux M.
AU - Devaux B.
AU - Refregiers M.
AU - Abi Haidar D.
PY - 2017
SP - 152
EP - 157
DO - 10.5220/0006103601520157