Preparation of a PLGA/Calcium Silicate Composite with Gradient Pore Structure

Bong-Kyu Choi, Suk Young Kim, Sang-Hoon Rhee

2013

Abstract

The PLGA/SiO2-CaO composite, which have a gradient pore structure, was newly prepared by the expansion of carbon dioxide gas in the PLGA matrix. The bioactive SiO2-CaO particles were made by a sol-gel method from tetraethyl orthosilicate and calcium nitrate tetrahydrate under acidic condition followed by the heat treatment at 600oC for 2 h. The PLGA/SiO2-CaO composite was then prepared by a solvent casting using chloroform as solvent. The composite was loaded into the high pressure chamber and then carbon dioxide gas was introduced achieving a final pressure of 10 MPa. After 3 days, the gas was released quickly and the gradient pore structure was developed. The samples were observed by FE-SEM and its bioactivity was tested in simulated body fluid.

References

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Paper Citation


in Harvard Style

Choi B., Young Kim S. and Rhee S. (2013). Preparation of a PLGA/Calcium Silicate Composite with Gradient Pore Structure . In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2013) ISBN 978-989-8565-34-1, pages 239-242. DOI: 10.5220/0004200302390242


in Bibtex Style

@conference{biodevices13,
author={Bong-Kyu Choi and Suk Young Kim and Sang-Hoon Rhee},
title={Preparation of a PLGA/Calcium Silicate Composite with Gradient Pore Structure},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2013)},
year={2013},
pages={239-242},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0004200302390242},
isbn={978-989-8565-34-1},
}


in EndNote Style

TY - CONF
JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2013)
TI - Preparation of a PLGA/Calcium Silicate Composite with Gradient Pore Structure
SN - 978-989-8565-34-1
AU - Choi B.
AU - Young Kim S.
AU - Rhee S.
PY - 2013
SP - 239
EP - 242
DO - 10.5220/0004200302390242