MULTIMODAL REGISTRATION OF NMR-VOLUMES AND HISTOLOGICAL CROSS-SECTIONS OF BARLEY GRAINS ON THE CELL BROADBAND ENGINE PROCESSOR

Rainer Pielot, Udo Seiffert, Bertram Manz, Diana Weier, Frank Volke, Falk Schreiber, Winfriede Weschke

2009

Abstract

Representation of developmental gradients in biological structures requires visualization of storage compounds, metabolites or mRNA hybridization patterns in a 3D morphological framework. NMR imaging can generate such a 3D framework by non-invasive scanning of living structures. Histology provides the distribution of developmental markers as 2D cross-sections. Multimodal alignment tries to put such different image modalities into correspondence. Here we compare different methods for rigid registration of 3D NMR datasets and 2D cross-sections of developing barley grains. As metrics for similarity measurements mutual information, cross correlation and overlap index are used. In addition, different filters are applied to the images before the alignment. The algorithms are parallelized, partially vectorized and implemented on the Cell Broadband Engine processor in a Playstation® 3. Evaluation is done by a comparison of the results to a manually defined gold standard of a NMR dataset and a corresponding 2D cross-section of the same grain. The results show, that best alignment is achieved by application of mutual information on sobel-filtered images and, compared to the implementation on a standard single-core CPU, the computation is accelerated by a factor up to 1.95.

References

  1. Butz, T., Thiran, J.-P., 2001. Affine registration with feature space mutual information. In Proceedings of the 4th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI' 01). 2208:549-556
  2. Haber, E., Modersitzki, J., 2004. Intensity gradient based registration and fusion of multi-modal images. In Technical Reports TR-2004-027-A 2004. Department of Mathematics and Computer Science, Emory University, Atlanta, GA
  3. Maes, F., Vandermeulen, D., Suetens, P., 2003. Medical image registration using mutual information. In Proceedings of the IEEE. 91(10):1699-1721
  4. Maintz, J.B.A., van den Elsen, P.A., Viergever, M.A., 1996. Comparison of edge-based and ridge-based registration of CT and MR brain images. Medical Image Analysis. 1(2):151-161
  5. Pluim, J.P.W., Maintz, J.B.A., Viergever, M.A., 2000. Image registration by maximization of combined mutual information and gradient information. IEEE Transaction on Medical Imaging. 19(8):809-814
  6. Pluim, J.P.W., Maintz, J.B.A., Viergever, M.A., 2003. Mutual information based registration of medical images: a survey. IEEE Transactions on Medical Imaging. 22:986-1004
  7. Thévenanz, P., Unser M., 2000. Optimization of mutual information for multiresolution image registration. IEEE Transactions on Image Processing. 9(12):2083- 2099
  8. Van den Elsen, P.A., Pol, E.J.D., Sumanaweera, T.S., Hemler, P., Napel, S., Adler, J., 1994. Grey value correlation techniques used for automatic matching of CT and MR brain and spine images. Visualization in Biomedical Computing. Vol. 2359 of Proceedings SPIE, SPIE Press, Bellingham, WA, pp. 227-237
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Paper Citation


in Harvard Style

Pielot R., Seiffert U., Manz B., Weier D., Volke F., Schreiber F. and Weschke W. (2009). MULTIMODAL REGISTRATION OF NMR-VOLUMES AND HISTOLOGICAL CROSS-SECTIONS OF BARLEY GRAINS ON THE CELL BROADBAND ENGINE PROCESSOR . In Proceedings of the Fourth International Conference on Computer Vision Theory and Applications - Volume 1: VISAPP, (VISIGRAPP 2009) ISBN 978-989-8111-69-2, pages 241-244. DOI: 10.5220/0001767102410244


in Bibtex Style

@conference{visapp09,
author={Rainer Pielot and Udo Seiffert and Bertram Manz and Diana Weier and Frank Volke and Falk Schreiber and Winfriede Weschke},
title={MULTIMODAL REGISTRATION OF NMR-VOLUMES AND HISTOLOGICAL CROSS-SECTIONS OF BARLEY GRAINS ON THE CELL BROADBAND ENGINE PROCESSOR},
booktitle={Proceedings of the Fourth International Conference on Computer Vision Theory and Applications - Volume 1: VISAPP, (VISIGRAPP 2009)},
year={2009},
pages={241-244},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0001767102410244},
isbn={978-989-8111-69-2},
}


in EndNote Style

TY - CONF
JO - Proceedings of the Fourth International Conference on Computer Vision Theory and Applications - Volume 1: VISAPP, (VISIGRAPP 2009)
TI - MULTIMODAL REGISTRATION OF NMR-VOLUMES AND HISTOLOGICAL CROSS-SECTIONS OF BARLEY GRAINS ON THE CELL BROADBAND ENGINE PROCESSOR
SN - 978-989-8111-69-2
AU - Pielot R.
AU - Seiffert U.
AU - Manz B.
AU - Weier D.
AU - Volke F.
AU - Schreiber F.
AU - Weschke W.
PY - 2009
SP - 241
EP - 244
DO - 10.5220/0001767102410244