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Authors: Łukasz Górski 1 ; Robert Ziółkowski 1 ; Elżbieta Malinowska 1 ; Piotr Prokaryn 2 and Michał Zaborowski 2

Affiliations: 1 Warsaw University of Technology and Faculty of Chemistry, Poland ; 2 Institute of Electron Technology, Poland

Keyword(s): Voltammetry, Vacuum deposited gold, DNA biosensors, Monolayers.

Related Ontology Subjects/Areas/Topics: Biomedical Engineering ; Biomedical Instruments and Devices ; Biomedical Sensors ; Microelectronics

Abstract: Silicon-based chips with vacuum deposited gold electrode were tested as transducers for the development of DNA-modified biosensors. It was found that these structures are superior over commercially available transducers, mainly due to perfectly smooth surface of gold working electrode. This was confirmed with microscopic and electrochemical experiments. Obtained transducers were modified with oligonucleotide self-assembled monolayer. These sensors were shown to detect chosen DNA sequence with the employment of methylene blue as a redox marker. The same sensors were used to determine UO22+ cation, however these efforts were unsuccessful.

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Paper citation in several formats:
Górski, Ł.; Ziółkowski, R.; Malinowska, E.; Prokaryn, P. and Zaborowski, M. (2011). SILICON-BASED GOLD TRANSDUCERS FOR DNA BIOSENSORS. In Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2011) - BIODEVICES; ISBN 978-989-8425-37-9; ISSN 2184-4305, SciTePress, pages 146-149. DOI: 10.5220/0003133901460149

@conference{biodevices11,
author={Łukasz Górski. and Robert Ziółkowski. and Elżbieta Malinowska. and Piotr Prokaryn. and Michał Zaborowski.},
title={SILICON-BASED GOLD TRANSDUCERS FOR DNA BIOSENSORS},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2011) - BIODEVICES},
year={2011},
pages={146-149},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0003133901460149},
isbn={978-989-8425-37-9},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the International Conference on Biomedical Electronics and Devices (BIOSTEC 2011) - BIODEVICES
TI - SILICON-BASED GOLD TRANSDUCERS FOR DNA BIOSENSORS
SN - 978-989-8425-37-9
IS - 2184-4305
AU - Górski, Ł.
AU - Ziółkowski, R.
AU - Malinowska, E.
AU - Prokaryn, P.
AU - Zaborowski, M.
PY - 2011
SP - 146
EP - 149
DO - 10.5220/0003133901460149
PB - SciTePress

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