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Authors: Anca Bucur 1 ; Jasper van Leeuwen 1 and Nevenka Dimitrova 2

Affiliations: 1 Philips Research Europe, Netherlands ; 2 Philips Research USA, United States

Keyword(s): Genomic signal processing, DNA spectral analysis, Spectral alignment, Frequency sorting, Distributed computing.

Related Ontology Subjects/Areas/Topics: Algorithms and Software Tools ; Bioinformatics ; Biomedical Engineering ; Data Mining and Machine Learning ; Genomics and Proteomics ; Sequence Analysis

Abstract: DNA spectral analysis, i.e. the analysis of DNA spectrograms, has been proposed as a method to systematically investigate DNA patterns, which may correspond to relevant biological features. The Frequency Sorting method sorts the sequences in spectral domain based on their frequency content, and detects and groups those sequences exhibiting one or more strong patterns in the same frequencies. In this paper we propose a novel distributed algorithm for Frequency Sorting and report on the performance results of our implementation for the alignment in spectral domain of the human chromosome 21. Distributed Frequency Sorting enables efficient spectral alignment and allows for the easy detection of strong patterns in both single and multiple frequencies.

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Paper citation in several formats:
Bucur, A.; van Leeuwen, J. and Dimitrova, N. (2010). DISTRIBUTED FREQUENCY SORTING IN SPECTRAL VIDEO ANALYSIS OF DNA SEQUENCES. In Proceedings of the First International Conference on Bioinformatics (BIOSTEC 2010) - BIOINFORMATICS; ISBN 978-989-674-019-1; ISSN 2184-4305, SciTePress, pages 207-210. DOI: 10.5220/0002713302070210

@conference{bioinformatics10,
author={Anca Bucur. and Jasper {van Leeuwen}. and Nevenka Dimitrova.},
title={DISTRIBUTED FREQUENCY SORTING IN SPECTRAL VIDEO ANALYSIS OF DNA SEQUENCES},
booktitle={Proceedings of the First International Conference on Bioinformatics (BIOSTEC 2010) - BIOINFORMATICS},
year={2010},
pages={207-210},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0002713302070210},
isbn={978-989-674-019-1},
issn={2184-4305},
}

TY - CONF

JO - Proceedings of the First International Conference on Bioinformatics (BIOSTEC 2010) - BIOINFORMATICS
TI - DISTRIBUTED FREQUENCY SORTING IN SPECTRAL VIDEO ANALYSIS OF DNA SEQUENCES
SN - 978-989-674-019-1
IS - 2184-4305
AU - Bucur, A.
AU - van Leeuwen, J.
AU - Dimitrova, N.
PY - 2010
SP - 207
EP - 210
DO - 10.5220/0002713302070210
PB - SciTePress