loading
Papers Papers/2022 Papers Papers/2022

Research.Publish.Connect.

Paper

Paper Unlock

Authors: Anderson Bihain 1 ; Antônio Silva Neto 2 and Leôncio Diógenes T. Câmara 2

Affiliations: 1 UNIPAMPA Federal University of Pampa, Brazil ; 2 IPRJ-UERJ Polytechnic Institute of the State University of Rio de Janeiro, Brazil

Keyword(s): Simulation Moving Bed, Inverse Problems, Modelling and Simulation, Chromatography.

Related Ontology Subjects/Areas/Topics: Application Domains ; Case Studies ; Chemical and Petroleum Engineering ; Conceptual Modeling ; Discrete-Event Simulation ; Dynamical Systems Models and Methods ; Formal Methods ; Health Engineering and Technology Applications ; Mathematical Simulation ; Neural Rehabilitation ; Neurotechnology, Electronics and Informatics ; Performance Analysis ; Simulation and Modeling ; Simulation Tools and Platforms

Abstract: The Simulated Moving Bed (SMB) is a countercurrent and continuum process that presents a high separation efficiency. It has been extensively applied in the separation of the petrochemical compounds, in the enantiomeric separation of racemic drugs, and in other mixtures that are difficult to separate. Currently the models used to predict the mass transport along chromatographic columns consist of systems of partial differential equations that presents a high computational cost. To modeling SMB process the novel approach Front Velocity is presented. This consists of ordinary differential equations and do not utilize adsorption isotherms, and therefore it is not necessary to perform equilibrium experiments, which are common procedures in classical modeling. The first stage of the research work was to characterize the chromatographic column, where the Random constraint window (R2W) algorithm was employed associate to a kinetic mass transfer equation of the new approach in the solution of the inverse problem. With the parameters obtained in the characterization of the chromatographic column, the SMB process simulation was performed, obtaining the separation profiles of the studied compounds. To validate the model developed, the simulated results were compared with experimental data of enantiomeric separation of the Ketamine, also confronted with the simulations obtained from classical models. The results show that the Front Velocity model has a reasonable agreement with experimental data. Likewise showed similar results to those separation profiles obtained by classical modeling using partial differential equations, requiring computational cost about twenty times smaller. (More)

CC BY-NC-ND 4.0

Sign In Guest: Register as new SciTePress user now for free.

Sign In SciTePress user: please login.

PDF ImageMy Papers

You are not signed in, therefore limits apply to your IP address 35.175.200.199

In the current month:
Recent papers: 100 available of 100 total
2+ years older papers: 200 available of 200 total

Paper citation in several formats:
Bihain, A.; Silva Neto, A. and Câmara, L. (2014). The Front Velocity Approach in the Modelling of Simulated Moving Bed Process (SMB). In Proceedings of the 4th International Conference on Simulation and Modeling Methodologies, Technologies and Applications - SIMULTECH; ISBN 978-989-758-038-3; ISSN 2184-2841, SciTePress, pages 5-11. DOI: 10.5220/0005009400050011

@conference{simultech14,
author={Anderson Bihain. and Antônio {Silva Neto}. and Leôncio Diógenes T. Câmara.},
title={The Front Velocity Approach in the Modelling of Simulated Moving Bed Process (SMB)},
booktitle={Proceedings of the 4th International Conference on Simulation and Modeling Methodologies, Technologies and Applications - SIMULTECH},
year={2014},
pages={5-11},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005009400050011},
isbn={978-989-758-038-3},
issn={2184-2841},
}

TY - CONF

JO - Proceedings of the 4th International Conference on Simulation and Modeling Methodologies, Technologies and Applications - SIMULTECH
TI - The Front Velocity Approach in the Modelling of Simulated Moving Bed Process (SMB)
SN - 978-989-758-038-3
IS - 2184-2841
AU - Bihain, A.
AU - Silva Neto, A.
AU - Câmara, L.
PY - 2014
SP - 5
EP - 11
DO - 10.5220/0005009400050011
PB - SciTePress