Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia

Septriyanto Dirgantara, Rosye H. R. Tanjung, Rahmawati Nurlatifah, Edy Meiyanto

2018

Abstract

Background: Some medicinal plants from Papua which have been used traditionally as anticancer agents for many ethnic in Papua Islands. But, scientific evidence for this study were still limited. Objective: The present study was conducted to test for in vitro Brine Shrimp Lethality Test (BSLT) of the seven selected medicinal plants from Papua, namely, Drymis piperita (local name : Kayu Akway), Myrmecodia beccarii (Sarang semut), Biophytum petersianum (Rumput kebar), Vernonia amygdalina (Daun Afrika),Villebrunea rubescens( Daun Jilat), Laportea aestuans (Daun Gatal) and Breynia cernua (Katuk hutan). Methods: Seven ethanolic extracts were evaluated for their cytotoxic activity against Artemia salina Leach with concentration extracts from 10;100; and 1000 μg/mL. Cytotoxicity was evaluated in terms of LC 50 value from the 24 hour counts using the probit analysis method. Results: Ethanolic extracts of Myrmecodia beccarii showed the highest cytotoxicity with LC 50 was 8.33 μg/mL against brine shrimp, but all selected medicinal plants showed the active potential cytotoxic activity because the LC 50 value were <1000 μg/mL. Conclusion: From this research, M.beccarii indicated the possible potential use of medicinal plants from Papua as anticancer agents.

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Paper Citation


in Harvard Style

Dirgantara S., Tanjung R., Nurlatifah R. and Meiyanto E. (2018). Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia.In Proceedings of BROMO Conference - Volume 1: BROMO, ISBN 978-989-758-347-6, pages 155-158. DOI: 10.5220/0008359001550158


in Bibtex Style

@conference{bromo18,
author={Septriyanto Dirgantara and Rosye H. R. Tanjung and Rahmawati Nurlatifah and Edy Meiyanto},
title={Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia},
booktitle={Proceedings of BROMO Conference - Volume 1: BROMO,},
year={2018},
pages={155-158},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0008359001550158},
isbn={978-989-758-347-6},
}


in EndNote Style

TY - CONF

JO - Proceedings of BROMO Conference - Volume 1: BROMO,
TI - Cytotoxic Activity of Selected Medicinal Plants from Papua, Indonesia
SN - 978-989-758-347-6
AU - Dirgantara S.
AU - Tanjung R.
AU - Nurlatifah R.
AU - Meiyanto E.
PY - 2018
SP - 155
EP - 158
DO - 10.5220/0008359001550158