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Authors: Guangyu Zhu 1 ; Masakazu Nakao 2 ; Qi Yuan 3 and Joon Hock Yeo 4

Affiliations: 1 Xi'an Jiaotong University and Nanyang Technological University, China ; 2 KK Women’s and Children’s Hospital, Singapore ; 3 Xi'an Jiaotong University, China ; 4 Nanyang Technological University, Singapore

ISBN: 978-989-758-216-5

Keyword(s): ePTFE, Artificial Heart Valve, Aortic Valve Replacement.

Related Ontology Subjects/Areas/Topics: Biomaterials ; Biomechanical Devices ; Biomedical Engineering ; Biomedical Instruments and Devices

Abstract: Truly stentless polymeric valve prosthesis can be a viable alternative for aortic valve replacement (AVR). In the present paper, the dynamic and hemodynamic performance of a novel designed expanded-polytetrafluoroethylene (ePTFE) stentless tri-leaflet valve was assessed experimentally. The in-vitro tests were performed under time-varying physiological pressure by using the Vivitro pulse duplicator. A high-speed camera, a flow meter, and pressure transducers were utilized to evaluate the dynamic leaflet behaviours and coaptation parameters. The maximum effective orifice area, mean pressure gradient, regurgitant volume, leakage volume and energy loss of the stentless ePTFE tri-leaflet valve are 2.86 cm2, 9.89 mmHg, 7.09 ml/beat, 2.81 ml/beat and 129.03 mJ, respectively. The results of the current study may provide a viable option for the future clinical application.

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Paper citation in several formats:
Zhu G., Nakao M., Yuan Q. and Yeo J. (2017). in-vitro Assessment of Expanded-Polytetrafluoroethylene Stentless Tri-leaflet Valve Prosthesis for Aortic Valve Replacement.In Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2017) ISBN 978-989-758-216-5, pages 186-189. DOI: 10.5220/0006184401860189

@conference{biodevices17,
author={Guangyu Zhu and Masakazu Nakao and Qi Yuan and Joon Hock Yeo},
title={in-vitro Assessment of Expanded-Polytetrafluoroethylene Stentless Tri-leaflet Valve Prosthesis for Aortic Valve Replacement},
booktitle={Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2017)},
year={2017},
pages={186-189},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0006184401860189},
isbn={978-989-758-216-5},
}

TY - CONF

JO - Proceedings of the 10th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 1: BIODEVICES, (BIOSTEC 2017)
TI - in-vitro Assessment of Expanded-Polytetrafluoroethylene Stentless Tri-leaflet Valve Prosthesis for Aortic Valve Replacement
SN - 978-989-758-216-5
AU - Zhu G.
AU - Nakao M.
AU - Yuan Q.
AU - Yeo J.
PY - 2017
SP - 186
EP - 189
DO - 10.5220/0006184401860189

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