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Authors: Sibylle Robens 1 ; Thomas Ostermann 1 ; Sebastian Unger 1 ; Petra Heymann 2 ; Stephan Müller 3 ; Christoph Laske 3 and Ulrich Elbing 2

Affiliations: 1 Department of Psychology and Psychotherapy, Witten/Herdecke University, Witten, Germany ; 2 Institut for Research and Development in Arts Therapies, Nürtingen-Geislingen University, Nürtingen, Germany ; 3 Department of Psychiatry and Psychotherapy, Eberhard Karls University, Tübingen, Germany

ISBN: 978-989-758-353-7

Keyword(s): Gray Level Co-occurrence Matrix, Digital Device, Alzheimer’s Disease Screening.

Abstract: Gray level co-occurrence texture characteristics of digital drawings were compared between persons with early dementia of Alzheimer’s disease and healthy controls. It was hypothesized that texture characteristics contribute to the differentiation between these subject groups. The study population consisted of 67 healthy subjects and 56 patients with early dementia of Alzheimer’s type. Between subject groups comparisons of texture entropy, homogeneity, correlation and image size were conducted with Mann-Whitney-U tests. The diagnostic power of combining all texture features as explanatory variables was analysed with a logistic regression model and the area under curve (AUC) of the corresponding receiver operating control (ROC) curve was calculated. The gray level co-occurrence characteristics differed significantly between healthy and demented subjects and the logistic regression model resulted in an AUC of 0.86 (95% CI [0.80, 0.93], sensitivity=.80, specificity=.79).

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Paper citation in several formats:
Robens S., Ostermann T., Unger S., Heymann P., Müller S., Laske C. and Elbing U. (2019). Digital Picture Co-occurrence Texture Characteristics Discriminate between Patients with Early Dementia of Alzheimer’s Type and Cognitive Healthy Subjects .In Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF, ISBN 978-989-758-353-7, pages 88-93. DOI: 10.5220/0007357500880093

@conference{healthinf19,
author={Sibylle Robens and Thomas Ostermann and Sebastian Unger and Petra Heymann and Stephan Müller and Christoph Laske and Ulrich Elbing},
title={Digital Picture Co-occurrence Texture Characteristics Discriminate between Patients with Early Dementia of Alzheimer’s Type and Cognitive Healthy Subjects },
booktitle={Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF,},
year={2019},
pages={88-93},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0007357500880093},
isbn={978-989-758-353-7},
}

TY - CONF

JO - Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies - Volume 5: HEALTHINF,
TI - Digital Picture Co-occurrence Texture Characteristics Discriminate between Patients with Early Dementia of Alzheimer’s Type and Cognitive Healthy Subjects
SN - 978-989-758-353-7
AU - Robens S.
AU - Ostermann T.
AU - Unger S.
AU - Heymann P.
AU - Müller S.
AU - Laske C.
AU - Elbing U.
PY - 2019
SP - 88
EP - 93
DO - 10.5220/0007357500880093

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