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Authors: Karine Charrière 1 ; Alain Rouleau 2 ; Olivier Gaiffe 2 ; Pascal Morel 3 ; Véronique Bourcier 1 ; Christian Pieralli 2 ; Wilfrid Boireau 2 ; Lionel Pazart 1 and Bruno Wacogne 4

Affiliations: 1 Besançon University Hospital, France ; 2 UMR CNRS 6174, France ; 3 Etablissement Français du Sang Bourgogne/Franche-Comté, France ; 4 Besançon University Hospital and UMR CNRS 6174, France

ISBN: 978-989-758-071-0

Keyword(s): Biosensor, Surface Plasmon Resonance, Human Red Blood Cells, Automated ABO Compatibility Test, Optical Detection, Opto-Fluidic Prototype.

Related Ontology Subjects/Areas/Topics: Biocomputing and Biochips ; Biomedical Engineering ; Biomedical Instrumentation ; Biomedical Instruments and Devices ; Biomedical Sensors

Abstract: In blood transfusion, accidents still occur because of ABO mismatch between donor and patient’s blood. These errors, sometimes lethal, are principally due to wrong identification of patient and/or blood product or to human errors. The best way to avoid these errors is to perform an ultimate ABO compatibility test at the patient’s bedside immediately prior to transfusion. Ideally, this test should be performed automatically, without human interpretation and with minimum blood exposure for nurses. This ideal and ultimate method is not yet employed because of the lack of suitable device. In this paper, we propose a system that may fulfil the above mentioned requirements. It is based on selective blood capture on biochip surfaces in a device which automatically drives the different fluids, performs optical detection of captured red cells and finally interprets the optical reading in terms of ABO compatibility. So far, our device achieved blood compatibility test with 99.3 % sensitivity an d 97.9 % specificity. (More)

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Paper citation in several formats:
Charrière K., Rouleau A., Gaiffe O., Morel P., Bourcier V., Pieralli C., Boireau W., Pazart L. and Wacogne B. (2015). An Automated Medical Device for Ultimate ABO Compatibility Test at the Patient’s Bedside - Towards the Automation of Point-of-care Transfusion Safety.In Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2015) ISBN 978-989-758-071-0, pages 58-67. DOI: 10.5220/0005248700580067

@conference{biodevices15,
author={Karine Charrière and Alain Rouleau and Olivier Gaiffe and Pascal Morel and Véronique Bourcier and Christian Pieralli and Wilfrid Boireau and Lionel Pazart and Bruno Wacogne},
title={An Automated Medical Device for Ultimate ABO Compatibility Test at the Patient’s Bedside - Towards the Automation of Point-of-care Transfusion Safety},
booktitle={Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2015)},
year={2015},
pages={58-67},
publisher={SciTePress},
organization={INSTICC},
doi={10.5220/0005248700580067},
isbn={978-989-758-071-0},
}

TY - CONF

JO - Proceedings of the International Conference on Biomedical Electronics and Devices - Volume 1: BIODEVICES, (BIOSTEC 2015)
TI - An Automated Medical Device for Ultimate ABO Compatibility Test at the Patient’s Bedside - Towards the Automation of Point-of-care Transfusion Safety
SN - 978-989-758-071-0
AU - Charrière K.
AU - Rouleau A.
AU - Gaiffe O.
AU - Morel P.
AU - Bourcier V.
AU - Pieralli C.
AU - Boireau W.
AU - Pazart L.
AU - Wacogne B.
PY - 2015
SP - 58
EP - 67
DO - 10.5220/0005248700580067

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